The protective effects of L-carnitine and resveratrol against alcohol-induced liver damage in Mus Musculus

• Main Authors: dela Cruz, Reanne Louise T., Oliveros, Kimberly Rosary S.T., Yap, Jennilyn J.
• Format: text
• Language: English
• Published: Animo Repository 2012
• Online Access: https://animorepository.dlsu.edu.ph/etd_bachelors/11771
• Institution: De La Salle University

Alcoholism is a major problem in the society. There are several food supplements that are claimed to protect liver from alcohol damage and disease. In this study, the effects of the food supplements L-carnitine and resveratrol on the livers of alcohol-treated male whit mice (Mus musculus) were examined. The mice were divided into six groups each consisting of five animals as follows: negative control (-), alcohol control (A), L-carnitine control (LC), resveratrol control (R) L-carnitine + alcohol treatment group (LC+A) and the resveratrol + alcohol treatment groups (R+A) and was treated for 10 days. The alcohol control livers (A) showed signs of severe damage in the sinusoids and hepatocytes. The L-carnitine (LC) and resveratrol (R) control groups showed no significant change as compared to the negative control (-). The L-carnitine + alcohol treatment (LC+A) showed no significant damage, as did the resveratrol + alcohol treatments (R+A). The results indicate a potential protective effect of the two food supplements against alcohol-induced liver damage.