The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans)

Miconazole is a broad-spectrum antimycot agent that has been proven to be effective in secondary mycoses caused by Candida albicans, a fungus resembling yeast causing fungal infection in man and animals. The study determined the safety and efficacy of topical antifungal miconazole in 21 rabbits. The...

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Main Author: Dizon, Charlotte Araza
Format: text
Language:English
Published: Animo Repository 1995
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Online Access:https://animorepository.dlsu.edu.ph/etd_bachelors/1279
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Institution: De La Salle University
Language: English
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spelling oai:animorepository.dlsu.edu.ph:etd_bachelors-22792021-06-14T08:25:35Z The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans) Dizon, Charlotte Araza Miconazole is a broad-spectrum antimycot agent that has been proven to be effective in secondary mycoses caused by Candida albicans, a fungus resembling yeast causing fungal infection in man and animals. The study determined the safety and efficacy of topical antifungal miconazole in 21 rabbits. The sample population was divided into three groups treated once, twice and thrice daily. Administration was done topically in a week with 3 hours daytime interval. Gross examination based on the percentage of adverse reactions and level of inhibation showed that once a day treatment was the safety and inhibited best the pathogenic activity of the fungus. Slow inhibition was attributed to the excessive use of miconazole observed in twice and trice daily treatment that produced edema and opacity due to hypersensitivity reaction. Finally, therapeutic safety, as measured by the spread between the effective dose and the dose at which slow adverse reactions begin to appear was significantly justified by the inhibitory performance of miconazole. 1995-01-01T08:00:00Z text https://animorepository.dlsu.edu.ph/etd_bachelors/1279 Bachelor's Theses English Animo Repository Antifungal agents Miconazole Mycoses Candida albicans Eye--Fungi Fungi Pathogenic Rabbits Funguous diseases
institution De La Salle University
building De La Salle University Library
continent Asia
country Philippines
Philippines
content_provider De La Salle University Library
collection DLSU Institutional Repository
language English
topic Antifungal agents
Miconazole
Mycoses
Candida albicans
Eye--Fungi
Fungi
Pathogenic
Rabbits
Funguous diseases
spellingShingle Antifungal agents
Miconazole
Mycoses
Candida albicans
Eye--Fungi
Fungi
Pathogenic
Rabbits
Funguous diseases
Dizon, Charlotte Araza
The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans)
description Miconazole is a broad-spectrum antimycot agent that has been proven to be effective in secondary mycoses caused by Candida albicans, a fungus resembling yeast causing fungal infection in man and animals. The study determined the safety and efficacy of topical antifungal miconazole in 21 rabbits. The sample population was divided into three groups treated once, twice and thrice daily. Administration was done topically in a week with 3 hours daytime interval. Gross examination based on the percentage of adverse reactions and level of inhibation showed that once a day treatment was the safety and inhibited best the pathogenic activity of the fungus. Slow inhibition was attributed to the excessive use of miconazole observed in twice and trice daily treatment that produced edema and opacity due to hypersensitivity reaction. Finally, therapeutic safety, as measured by the spread between the effective dose and the dose at which slow adverse reactions begin to appear was significantly justified by the inhibitory performance of miconazole.
format text
author Dizon, Charlotte Araza
author_facet Dizon, Charlotte Araza
author_sort Dizon, Charlotte Araza
title The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans)
title_short The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans)
title_full The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans)
title_fullStr The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans)
title_full_unstemmed The efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (Candida albicans)
title_sort efficacy and safety of topical antifungal miconazole cream in the treatment of corneal fungal infection, (candida albicans)
publisher Animo Repository
publishDate 1995
url https://animorepository.dlsu.edu.ph/etd_bachelors/1279
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