Cutaneous inflammatory response in the rabbit using a modified rebuck skin window technique

• Main Author: Tan, Remy A.
• Format: text
• Language: English
• Published: Animo Repository 1996
• Subjects: Skin > Inflammation; Rabbits; Staphylococcal disease; Skin test
• Online Access: https://animorepository.dlsu.edu.ph/etd_bachelors/1391
• Institution: De La Salle University

Inflammatory cell populations were serially observed from uninfected skin abrasions and from lesions infected with Staphylococcus aureus in rabbits using a modified Rebuck skin window technique. Differential WBC counts showed that there was a generally higher neutrophil count in staphylococcal infection at all times, as compared to that in the uninfected lesion. Also, in staphylococcal infection, the neutrophil was always the predominant cell. For the uninfected lesion, it is the lymphocyte which predominates. It was also observed that in both lesions, the WBC counts increased over time up to a certain point, after which the total WBC counts generally decreased.