Effects of Caesalpinia sappan, sibucao wood decoction on the red blood cell count, hemoglobin concentration and hematocrit of Swiss mice
A study was conducted to determine the effects of Caesalpinia sappan (sibucao) wood decoction on RBC count, hemoglobin and hematocrit of male Swiss mice. Eighteen male mice were divided into 3 groups with 3 replicates and 3 controls. Treated mice were force-fed with decoction after the initial blood...
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| Format: | text |
| Language: | English |
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Animo Repository
1997
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| Online Access: | https://animorepository.dlsu.edu.ph/etd_bachelors/1423 |
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| Institution: | De La Salle University |
| Language: | English |
| Summary: | A study was conducted to determine the effects of Caesalpinia sappan (sibucao) wood decoction on RBC count, hemoglobin and hematocrit of male Swiss mice. Eighteen male mice were divided into 3 groups with 3 replicates and 3 controls. Treated mice were force-fed with decoction after the initial blood tests. The first group received 1 ml/kg body weight, the second with 1.5 ml/kg body weight and the third with 2 ml/kg body weight of wood decoction. Control mice were force-fed with water. Blood test were conducted at the start of the experiment and every seven days for 2 consecutive weeks of administration of decoction. As the concentration of decoction is increased and as administration is prolonged, the 3 groups of mice significantly increase their RBC count, hemoglobin and hematocrit. The mice group given 2 ml/kg decoction had the greatest increase in RBC count, from 5.5 M/mm to 6.2 M/mm. Hemoglobin content initially was 198.33 g/L and then went up to 231.67 g/L. Hematocrit increased from 53.67 % to 63.33 %. |
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