Drug susceptibility patterns and conjugative transferability of drug resistance in Acinetobacter anitratum from patients of the Philippine General Hospital

• Main Author: Madson, Ma. Carla A.
• Format: text
• Language: English
• Published: Animo Repository 1997
• Subjects: Antibiotics > Testing; Drug resistance in microorganisms; Microorganisms > Effect of drugs on; Philippine General Hospital; Microbial metabolites
• Online Access: https://animorepository.dlsu.edu.ph/etd_bachelors/1449
• Institution: De La Salle University

Acinetobacter anitratum isolates from patients of the Philippine General Hospital were studied for their drug susceptibility patterns and transferability of their drug resistance to E. coli SF-800 by conjugation. Twenty four of the 25 isolates were resistant to at least one of the following test drugs, namely: ampicillin with sulbactam, amikacin, gentamicin, tobramycin, trimethoprim-sulfamethoxazole and nalidixic acid. Eighteen of the 25 isolates showed multiple resistance, some to as many as five drugs. Results for the conjugation showed that all isolates tested were able to transfer their resistance genes to E. coli SF-800 which served as the recipient. Only one isolate, isolate no. 8, can be said to have completely transferred only some of their resistance genes.