Protective effects of vitamin C and E supplementation against alcoholic fatty liver in Mus musculus (Albino mice)

• Main Authors: Carlos, Jason Thomas S., Dumo, Ted Julius R.
• Format: text
• Language: English
• Published: Animo Repository 2010
• Subjects: Vitamin C > Therapeutic use; Vitamin E; Fatty liver > Prevention; Animal Sciences; Biology
• Online Access: https://animorepository.dlsu.edu.ph/etd_bachelors/5580
• Institution: De La Salle University

Alcohol consumption has many harmful effects in body especially in the liver. Vitamins, on the other hand, are known to have essential roles in maintaining certain organs. In this study, the protective effect of vitamins C and E against fatty liver induced by excessive alcohol consumption was investigated. Thirty six male albino mice (Mus musculus) were divided into four groups (control, alcohol control, vitamin control and vitamins C and E plus alcohol). Moderate and severely steatotic cells were significantly higher among the alcohol control group compared to the other groups. On the other hand, the control, the vitamin control and the vitamins C and E plus alcohol administered groups mostly showed normal and mildly steatotic liver cells. This shows that vitamins C and E plus alcohol administered groups had lower risks in having steatotic cells compared to that of the alcohol control group. Because of this, vitamins C and E did have a protective effect against alcohol induced mice fatty liver.