Comparison of the minimum inhibitory concentration of expired and unexpired antibacterial agents on Escherichia coli and Staphylococcus aureus

• Main Authors: Buendia, Flynn M., Madrazo, Virgilio R.
• Format: text
• Language: English
• Published: Animo Repository 1998
• Subjects: Antibacterial agents; Antibiotics > Testing; Microbial sensitivity tests; Microorganisms > Effect of antibiotics on; Escherichia coli; Staphylococcus aureus
• Online Access: https://animorepository.dlsu.edu.ph/etd_bachelors/5912
• Institution: De La Salle University

Three-month expired antibacterial agents were tested for their minimum inhibitory concentration against Escherichia coli and Staphylococcus aureus. The antibacterial agents were: ampicillin/cloxacillin, amoxicillin/clavulanic acid, cefixime, chloramphenicol, and penicillin. Results showed that the minimum inhibitory concentrations of the expired antibacterial agents were different from the unexpired ones. But statistically there was no significant difference between the two sets of data except for chloramphenicol against S. aureus. It can be said that ampicillin/cloxacillin, amoxicillin/clavulanic acid, cefixime, and penicillin are still considered potent against E. coli and S. aureus infections even after three months of its expiry date. Chloramphenicol is still considered potent against E. coli infections only.