Toxicity, bioaccumulation and histopathological studies of Tilapia nilotica following sublethal exposure to carbaryl.

• Main Author: Salem, James Gregory C.
• Format: text
• Published: Animo Repository 1993
• Subjects: Tilapia.; Carbaryl.; Insecticides > Toxicology.
• Online Access: https://animorepository.dlsu.edu.ph/etd_doctoral/1336
• Institution: De La Salle University

The 96-hour LC50 of carbaryl to three month-old Tilapia nilotica was determined at 8.29 mg/l. The sublethal concentration of 6.22 mg/l (75 of 96-hour LC50 carbaryl) was used for the bioaccumulation and histopathological studies.Mean carbaryl residues (mg/l) were found highest in the treated pre-starved liver (12.79), followed by kidney (8.70) and lowest in the brain (0.59). Residue of the insecticide was found highest in the treated fed muscle (4.88 mg/l).Swollen and vacuolated hepatocytes and dilated sinusoids were noted in carbaryl-treated liver. Some arterial walls in treated pre-started liver showed shrinkage. Epithelial cells of the portal vein and bile duct remained intact. Glomerular degeneration and distention of the capsular space were observed in carbaryl-exposed tilapia. No histological changes in the brain of both treated and fed and treated pre-starved T. nilotica were found following carbaryl intoxication.