Triterpenes and a flavonoid from citrus microcarpa

• Main Author: Sia, Jennifer Escano
• Format: text
• Language: English
• Published: Animo Repository 2006
• Subjects: Triterpenoid saponins > Philippines; Flavonoids > Philippines; Citrus fruits > Research > Philippines; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/3398; https://animorepository.dlsu.edu.ph/context/etd_masteral/article/10236/viewcontent/CDTG004075_P.pdf
• Institution: De La Salle University

Dried leaves of the Philippines Citrus microcarpa Bunge1, commonly known as Calamansi, was studied for its secondary metabolites. The dichloromethane leaf extract of Citrus microcarpa afforded 3, 4, 5, 6, 7, 8 - Hexamethoxyflavone2 (KL-1), squalene (KL-3), and its derivative (KL-2). The structure of the flavone was elucidated by extensive 1-D and 2-D NMR, IR and UV spectroscopy, while squalene was identified by comparison of its 1H-NMR spectral data with those reported in literature. The proposed structure for the squalene derivative resulted from spectral comparison of the two compounds. The antimicrobial potential of the compound KL-1 was determined.