Flavonoids from Chromolaena odorata (Linn.) King & H. Rob

• Main Author: Cuarto, Ceazar Ryan Umali
• Format: text
• Language: English
• Published: Animo Repository 2007
• Subjects: Flavonoids; Chromolaena odorata; Dichloromethane
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/3483; https://animorepository.dlsu.edu.ph/context/etd_masteral/article/10321/viewcontent/CDTG004227_P.pdf
• Institution: De La Salle University

Chromolaena odorata (Linn.) King & H. Rob. afforded 5,6,7,4- tetramethoxyflavone (C-14) and 4-hydroxy-5,6,7-trimethoxyflavanone (C-16). The structures of the two flavonoids were elucidated by extensive 1D and 2D NMR spectroscopy. The structure of C-16 was confirmed by comparison of its 1H NMR spectral data with those reported in the literature. C-14 was tested for antimicrobial potential by the agar well method against seven microorganisms. Results of the study indicated low antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and low antifungal activity against Candida albicans and Trichophyton mentagrophytes. It was found inactive against Bacillus subtilis and Aspergillus niger.