Chromomoric acids from Tectona Philippinensis benth and hook and triterpenes from Emilia sonchifolia Linn

• Main Author: Espineli, Dinah L.
• Format: text
• Language: English
• Published: Animo Repository 2007
• Subjects: Dichloromethane; Tectona; Teak > Philippines; Tectona philippinensis; Emilia Sonchifolia Linn; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/3507; https://animorepository.dlsu.edu.ph/context/etd_masteral/article/10345/viewcontent/CDTG004321_P.pdf
• Institution: De La Salle University

Two plants, Tectona philippinensis Benth and Hook, locally known as Philippine Teak, and Emilia sonchifolia Linn, commonly known as tagulinaw, were studied for their chemical constituents. The air-dried leaves of Tectona philippinensis Benth and Hook from Iling Island, Mindoro afforded two new diastereomeric chromomoric acid derivatives by silica gel chromatography. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Preliminary testing revealed that the diastereomers active in lowering blood glucose level in rats at 2.0 mg / 200 g body weight. Air dried aerial parts of Emilia sonchifolia Linn afforded a mixture of taraxasteryl acetate and lupeol acetate in a 2:1 ratio by silica gel column chromatography. The structures of these compounds were elucidated by extensive 1D and 2D NMR spectroscopy.