Chromosomal aberrations and molecular changes in BCR-ABL gene in Chronic Myelogenous Leukemia (CML) patients undergoing chemotherapy

• Main Author: Soriano-Abad, Ma. Celeste S.
• Format: text
• Language: English
• Published: Animo Repository 2010
• Subjects: Chronic myeloid leukemia; Chemotherapy; Immunology and Infectious Disease
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/3838; https://animorepository.dlsu.edu.ph/cgi/viewcontent.cgi?article=10676&context=etd_masteral
• Institution: De La Salle University

Chronic myelogenous leukemia (CML) is the first cancer known to be associated with reciprocal translocation between chromosomes 9 and 22, t(9;22)(q34;q11). Monitoring of the disease is important to detect early evidence of residual malignant cells (MRD). The aim of the study is to identify cytogenet...