Synthesis, characterization, and In Vitro antimycobacterial activity evaluation of phthalimide derivatives

• Main Author: Paraiso, West Kristian D.
• Format: text
• Language: English
• Published: Animo Repository 2012
• Subjects: Tuberculosis; Hybridization—Molecular aspects; Molecular genetics; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/4111; https://animorepository.dlsu.edu.ph/context/etd_masteral/article/10949/viewcontent/CDTG005107_P.pdf
• Institution: De La Salle University

Phthalimide derivatives were synthesized using the concept of molecular hybridization or combination of two pharmacophores in one drug. Four new phthalimides were successfully prepared using a single-step condensation reaction between phthalic anhydride and four different sulfonamides. One previousl...