Synthesis of cholic acid-terminated dendritic lysine block - poly(ethylene glycol)-block - dendritic lysine for paclitaxel delivery
Paclitaxel, a chemotherapeutic drug used to inhibit mitosis in cancer cells, requires the use of the solubilizer Cremophor EL due to its poor water solubility. However, Cremophor EL is associated with adverse reactions following chemotherapy. This study aimed to synthesize an alternative solubilizin...
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Format: | text |
Language: | English |
Published: |
Animo Repository
2014
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Online Access: | https://animorepository.dlsu.edu.ph/etd_masteral/4628 |
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Institution: | De La Salle University |
Language: | English |