Detection and characterization of mutation in mismatch repair genes in a filipino family with HNPCC (Hereditary Nonpolyposis Colorectal Cancer)
Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal syndrome largely caused by germline mutations in any of the six mismatch repair genes. Eighty per cent of the reported cases are attributed to mutations in two MMR genes: hMLH1 and hMSH2. Mutation carriers exhibit a characteristic phe...
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| Format: | text |
| Language: | English |
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Animo Repository
2004
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| Online Access: | https://animorepository.dlsu.edu.ph/etd_masteral/5861 https://animorepository.dlsu.edu.ph/context/etd_masteral/article/12709/viewcontent/TG03817_F_Partial.pdf |
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| Institution: | De La Salle University |
| Language: | English |