Secondary metabolites from Glinus oppositifolius

• Main Author: Buluran, Adiel Inah L.
• Format: text
• Language: English
• Published: Animo Repository 2012
• Subjects: Metabolites; Glinus oppositifolius—Analysis; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/6912
• Institution: De La Salle University

The dichloromethane extract of the air-dried stems of Glinus oppositifolius (syn. Mollugo spergula and Mollugo oppositifolia) afforded spergulagenin A and squalene by silica gel chromatography. The structure of spergulagenin A was elucidated by extensive 1D and 2D NMR spectroscopy. This is the first report on the isolation of spergulagenin A from the stems and the first complete 1H and 13C NMR assignments of the compound. Squalene was identified by comparison of its 1H NMR spectral data with those found in the literature. The dichloromethane extract of the air-dried leaves of G. oppositifolius afforded lutein, spinasterol, phytol, squalene, oppositifolone, and oleanolic acid by silica gel chromatography. Lutein, oleanolic acid, and oppositifolone were identified by comparison of their 1H NMR and 13C NMR spectral data with those found in the literature. Spinasterol, phytol, and squalene were identified by comparison of their 1H NMR spectral data with those found in the literature. This is the first reported isolation of phytol from the plant. The air-dried roots of G. oppositifolius afforded spinasterol by silica gel chromatography. Spinasterol was identified by comparison of its 1H NMR spectral data with those found in the literature.