Isolation, structure elucidation, and antimicrobial screening of a terpene from a soft coral Sarcophyton sp
A cembranoid diterpene was isolated from a Philippine soft coral of genus Sarcophyton. The terpene was obtained from the chloroform extract of the soft coral by Vacuum Liquid Chromatography (vic). The structure of the isolate was elucidated by analyses of its spectral data from infrared (IR) and Hig...
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| Format: | text |
| Language: | English |
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Animo Repository
1995
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| Online Access: | https://animorepository.dlsu.edu.ph/etd_masteral/1672 https://animorepository.dlsu.edu.ph/cgi/viewcontent.cgi?article=8510&context=etd_masteral |
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| Institution: | De La Salle University |
| Language: | English |
| Summary: | A cembranoid diterpene was isolated from a Philippine soft coral of genus Sarcophyton. The terpene was obtained from the chloroform extract of the soft coral by Vacuum Liquid Chromatography (vic). The structure of the isolate was elucidated by analyses of its spectral data from infrared (IR) and High Field Nuclear Magnetic Resonance (NMR) spectroscopy such as 1H, 1H Decoupling, 13C, and DEPT-13C. The molecular formula of the isolate is C20H30O2. It is a new stereoisomer of known terpenes previously obtained from Sarcophyton. The isolate showed different levels of antimicrobial activity against seven microorganisms: Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Mycobacterium avium, Escherichia coli, Saccharomyces cerevisiae, and Aspergillus niger. |
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