Synthesis of D-galactose modified 1,3-dithiole-2-thione derivative

• Main Author: Quibilan, Jose Mari dela Cruz
• Format: text
• Language: English
• Published: Animo Repository 1997
• Subjects: Organic compounds—Synthesis; Organic semiconductors; Galactose; Infrared spectra; Spectrum analysis; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/1812; https://animorepository.dlsu.edu.ph/cgi/viewcontent.cgi?article=8650&context=etd_masteral
• Institution: De La Salle University

A procedure for the synthesis of a D-galactose modified 1,3-dithiole-2-thione derivative is described. D-galactose is converted to 1,2:3,4-di-O-isopropylidene-D-galactopyranose, which is esterified with trifluoromethanesulfonic anhydride. The triflate ester is then treated 2-hydroxyethoxide followed by the tosylation of the hydroxyethylene derivative. The target compound is obtained by replacement of the tosylate with the zinc complex of 4,5-dimercapto-1,3-dithiole-2-thione dianion salt.