Detection of Philadelphia chromosome by GTG-banding technique and bcr-abl fusion gene by reverse-transcription polymerase chain reaction for chronic myelogenous leukemia: A study of 29 patients

• Main Author: Amarillo, Ferdinand Enginco
• Format: text
• Language: English
• Published: Animo Repository 2001
• Subjects: Leukemia > Diagnosis; Cytogenetics; Chromosome banding; Chromosomes > Analysis; Biology; Biotechnology
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/2533; https://animorepository.dlsu.edu.ph/cgi/viewcontent.cgi?article=9371&context=etd_masteral
• Institution: De La Salle University

Chronic myelogenous leukemia (CML) is a unique myeloproliferative disorder usually associated with a distinctive cytogenetic abnormality, the Philadelphia (Ph) chromosome and the bcr-abl fusion gene that leads to leukemogenesis. Cytogenetic analysis using GTG-banding (G-bands by Trypsin using Giemsa...