A computational approach on the interactions between sponge-derived bioactive compounds and the GTP-pocket in the methyltransferase domain of the NS5 protein from dengue virus serotype 3

• Main Authors: Pascua, Beatrice Paula G., Casiguran, Samantha Louise
• Format: text
• Language: English
• Published: Animo Repository 2023
• Subjects: Dengue viruses; Methyltransferases; Bioactive compounds; Molecular dynamics; Biochemistry; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/etdb_chem/43; https://animorepository.dlsu.edu.ph/context/etdb_chem/article/1046/viewcontent/2024_Pascua_Casiguran_A_Computational_Approach_on_the_Interactions_between_Sponge_deriv.pdf
• Institution: De La Salle University

Dengue, a mosquito-borne disease predominantly transmitted by Aedes mosquitoes, has emerged as a significant public health concern, affecting nearly half of the global population. Unfortunately, there is still no specific treatment and prevention for dengue. In line with that, bioactive compounds fr...