In silico assessment of moringa oleifera as an antiviral agent against the N501Y mutation in the receptor-binding domain of the spike glycoprotein of SARS-Cov-2 South African variant (B.1.351)

• Main Authors: Bracamonte, Patricia Bianca Romaraog, Gabay, Adrienne Chelsea Calaquian, Virtucio, Mianne Villanueva
• Format: text
• Language: English
• Published: Animo Repository 2022
• Subjects: Moringa oleifera; Antiviral agents; Physics
• Online Access: https://animorepository.dlsu.edu.ph/etdb_physics/7; https://animorepository.dlsu.edu.ph/context/etdb_physics/article/1002/viewcontent/2022_Bracamonte_Gabay_Virtucio_In_silico_assessment_of_Moringa_oleifera_Full_text.pdf
• Institution: De La Salle University

An in-silico method was employed to predict which of the fifteen Moringa oleifera phytocompounds would exhibit inhibitory action towards the spike glycoprotein with N501Y mutation of the SARS-CoV-2 B.1.351 variant. The phytocompounds were screened for their drug-likeness and Absorption, Distribution...