In silico study on the protein-protein interaction of D-dimer and glycoprotein VI in blood plasma as potential biomarker of ischemic stroke

• المؤلفون الرئيسيون: de Ramos, Brenna R., Ruivivar, Katrina Fatima B.
• التنسيق: text
• اللغة: English
• منشور في: Animo Repository 2022
• الموضوعات: Protein-protein interactions; Glycoproteins; Blood plasma; Physics
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/etdb_physics/15; https://animorepository.dlsu.edu.ph/context/etdb_physics/article/1020/viewcontent/2022_Ramos_Ruivivar_In_Silico_Study_on_the_Protein_Protein_Interaction_of_D_dimer_Full_text.pdf

This study used an in-silico approach to investigate the molecular interaction between D-dimer and Glycoprotein VI (GPVI) in blood plasma as a potential biomarker for ischemic stroke. GPVI underwent structural validation through Ramachandran Plot, ERRAT, and Verify 3D. Preliminary results showed tha...