Synthesis of glucosamine-conjugated metal complexes for anticancer and anti-metastatic targeted therapy

Synthesis of glucosamine-conjugated metal complexes for anticancer and anti-metastatic targeted therapy

Platinum and palladium complexes of the Schiff base of glucosamine and 8-hydroxy-2- quinolinecarboxaldehyde (OQN) were synthesized by the reaction of either Pt(DMSO)iCb or Na2PdCl4 in methanol with the ligand. Single crystal X-ray diffraction analysis revealed that these complexes form different dim...

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Bibliographic Details
Main Authors: Alba, Laurenzo De Vera, Hatanaka, Tsubasa, Nakai, Misaki, Yano, Shigenobu, Funahashi, Yasuhiro
Format: text
Published: Animo Repository 2018
Subjects:
Glucosamine—Synthesis
Metal complexes
Cancer—Treatment
Chemistry
Online Access:https://animorepository.dlsu.edu.ph/faculty_research/11264
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Institution: De La Salle University
Description
Summary:Platinum and palladium complexes of the Schiff base of glucosamine and 8-hydroxy-2- quinolinecarboxaldehyde (OQN) were synthesized by the reaction of either Pt(DMSO)iCb or Na2PdCl4 in methanol with the ligand. Single crystal X-ray diffraction analysis revealed that these complexes form different dimeric structures with TI-TI stacking and metal-metal interactions in the solid states.

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