Involvement of two microRNAs in the early immune response to DNA vaccination against a fish rhabdovirus

• Main Authors: Bela-ong, Dennis B., Schyth, Brian Dall, Zou, Jun, Secombes, Christopher J., Lorenzen, Niels
• Format: text
• Published: Animo Repository 2015
• Subjects: MicroRNA; Rhabdoviruses; DNA vaccines; Trout —Virus diseases; Biology; Biotechnology
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/11559
• Institution: De La Salle University

Mechanisms that account for the high protective efficacy in teleost fish of a DNA vaccine expressing the glycoprotein (G) of Viral hemorrhagic septicemia virus (VHSV) are thought to involve early innate immune responses mediated by interferons (IFNs). Microribonucleic acids (miRNAs) are a diverse cl...