Targeted next generation sequencing of the entire vitamin D receptor gene reveals polymorphisms correlated with vitamin D deficiency among older Filipino women with and without fragility fracture

• Main Authors: Zumaraga, Mark Pretzel, Medina, Paul Julius, Recto, Juan Miguel, Abrahan, Lauro, Azurin, Edelyn, Tanchoco, Celeste C., Jimeno, Cecilia A., Saloma, Cynthia Palmes
• Format: text
• Published: Animo Repository 2017
• Subjects: Vitamin D; Vitamin D deficiency; Vitamin D in human nutrition; Women—Nutrition—Philippines; High-throughput nucleotide sequencing
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/11467
• Institution: De La Salle University

This study aimed to discover genetic variants in the entire 101 kB vitamin D receptor (VDR) gene for vitamin D deficiency in a group of postmenopausal Filipino women using targeted next generation sequencing (TNGS) approach in a case–control study design. A total of 50 women with and without osteopo...