Virtual screening against mycobacterium tuberculosis lipoate protein ligase B (MtbLipB) and in silico ADMET evaluation of top hits

The emergence of drug resistant strains of Mycobacterium tuberculosis(Mtb) has spurred the search for new therapeutic targets for the development of more efficient anti-tuberculosis drugs. Lipoate protein ligase B (LipB), an enzyme involved in the biosynthesis of the lipoic acid cofactor, is conside...

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Bibliographic Details
Main Authors: Billones, Junie B., Carrillo, Maria Constancia O., Organo, Voltaire G., Macalino, Stephani Joy Y., Emnacen, Inno A., Sy, Jamie Bernadette A.
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Published: Animo Repository 2013
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/11461
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Institution: De La Salle University