Exercise-induced mitochondrial adaptations in addressing heart failure

Mitochondria are complex organelles essential for the production of energy. These dynamic, complex organelles found in every cell and tissues of the body have been well-studied in various physiological models, stressing that mitochondrial dysfunction is characteristic of pathological states, especia...

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Main Authors: Marquez, Jubert, Han, Jin
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Published: Animo Repository 2017
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/11530
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Institution: De La Salle University
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spelling oai:animorepository.dlsu.edu.ph:faculty_research-117332024-03-18T02:30:50Z Exercise-induced mitochondrial adaptations in addressing heart failure Marquez, Jubert Han, Jin Mitochondria are complex organelles essential for the production of energy. These dynamic, complex organelles found in every cell and tissues of the body have been well-studied in various physiological models, stressing that mitochondrial dysfunction is characteristic of pathological states, especially in cardio-vascular diseases and heart failure. Since heart failure progresses due to energy deficits brought about by altered mitochondrial bioenergetics and functioning, novel ways of ameliorating mitochondrial dysfunction are being studied. Interestingly, various exercise modalities can serve as stimuli which can regulate the mitochondria in different ways, such as in the increase of mitochondrial mass and copy number, in the structural fusion and fission processes, and the removal of impaired mitochondria. Considering that there are numerous kinds and protocols for exercise, there are a number of ways exercise can affect the mitochondria as well. Nonetheless these processes affect each other to an extent, highlighting the pivotal role exercise plays in improving or enhancing the state of mitochondria during disease. This chapter will focus on how exercise of different can regulate mitochondrial processes, which could be used as therapeutic strategies in addressing heart failure. 2017-01-01T08:00:00Z text https://animorepository.dlsu.edu.ph/faculty_research/11530 info:doi/DOI 10.1007/978-981-10-4304-8_17 Faculty Research Work Animo Repository Mitochondria Heart failure MicroRNA Cardiovascular Diseases
institution De La Salle University
building De La Salle University Library
continent Asia
country Philippines
Philippines
content_provider De La Salle University Library
collection DLSU Institutional Repository
topic Mitochondria
Heart failure
MicroRNA
Cardiovascular Diseases
spellingShingle Mitochondria
Heart failure
MicroRNA
Cardiovascular Diseases
Marquez, Jubert
Han, Jin
Exercise-induced mitochondrial adaptations in addressing heart failure
description Mitochondria are complex organelles essential for the production of energy. These dynamic, complex organelles found in every cell and tissues of the body have been well-studied in various physiological models, stressing that mitochondrial dysfunction is characteristic of pathological states, especially in cardio-vascular diseases and heart failure. Since heart failure progresses due to energy deficits brought about by altered mitochondrial bioenergetics and functioning, novel ways of ameliorating mitochondrial dysfunction are being studied. Interestingly, various exercise modalities can serve as stimuli which can regulate the mitochondria in different ways, such as in the increase of mitochondrial mass and copy number, in the structural fusion and fission processes, and the removal of impaired mitochondria. Considering that there are numerous kinds and protocols for exercise, there are a number of ways exercise can affect the mitochondria as well. Nonetheless these processes affect each other to an extent, highlighting the pivotal role exercise plays in improving or enhancing the state of mitochondria during disease. This chapter will focus on how exercise of different can regulate mitochondrial processes, which could be used as therapeutic strategies in addressing heart failure.
format text
author Marquez, Jubert
Han, Jin
author_facet Marquez, Jubert
Han, Jin
author_sort Marquez, Jubert
title Exercise-induced mitochondrial adaptations in addressing heart failure
title_short Exercise-induced mitochondrial adaptations in addressing heart failure
title_full Exercise-induced mitochondrial adaptations in addressing heart failure
title_fullStr Exercise-induced mitochondrial adaptations in addressing heart failure
title_full_unstemmed Exercise-induced mitochondrial adaptations in addressing heart failure
title_sort exercise-induced mitochondrial adaptations in addressing heart failure
publisher Animo Repository
publishDate 2017
url https://animorepository.dlsu.edu.ph/faculty_research/11530
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