Chemical constituents of Dracontomelon Dao (Blanco) Merr. et Rolfe

• Main Authors: Ragasa, Consolacion Y., Batarra, Tyson C., Vivar, Julius Leonard A., De Los Reyes, Mariquit M., Shen, Chien Chang
• Format: text
• Published: Animo Repository 2017
• Subjects: Spondias—Composition; Spondias—Philippines; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/365; https://animorepository.dlsu.edu.ph/context/faculty_research/article/1364/type/native/viewcontent
• Institution: De La Salle University

Introduction: The leaves, twigs and flowers of Dracontomelon dao (Blanco) Merr. et Rolfe, an indigenous Philippine tree were investigated for their chemical constituents. Methods: The compounds were isolated by silica gel chromatography and their structures were identified by NMR spectroscopy. Results: Chemical investigation of D. dao led to the isolation of cardol (1), β-sitosteryl-3β-glucopyranoside-6, O-fatty acid esters (2), β-sitosteryl fatty acid esters (3), and a mixture of β-sitosterol (4a) and stigmasterol (4b) from the petiole; 1, a mixture of 4a and 4b, anacardic acid (5), triacylglycerols (6), monoacylglycerol (7), long-chain fatty acid esters (8), and linoleic acid (9) from the twigs; and a mixture of 4a and 4b, 5, 6, 8, long-chain fatty alcohols (10), and long- chain hydrocatbons (11) from the flowers of D. dao.The structures of 1 and 5 were elucidated by extensive 1D and 2D NMR spectroscopy, while those of 2-4 and 6-11 were identified by NMR spectroscopy. Conclusion: This is the first report on the isolation of 1, 4b and 6-9 from D. dao. Key words: Dracontomelon Dao (Blanco) Merr. et Rolfe, Anacardaceae, Cardol, Anacardic Acid, 3-Alkylphenols, B-Sitosteryl-3β-Glucopyranoside-6'-O-Fatty Acid Esters, B-Sitosteryl Fatty Acid Esters. © 2017 Phcog.Net.