Antibiograms of nosocomial staphylococcal isolates from Philippine General Hospital in the first quarter of 2001

• Main Authors: Lee, Anthony C., Cantiller, Patricio Elvin L., Esquivel, Veradette Vianca C., Rodriguez, Roselyn D.
• Format: text
• Published: Animo Repository 2003
• Subjects: Anti-infective agents; Staphylococcus; Staphylococcal infections; Microbiology
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/13177
• Institution: De La Salle University

The antibiograms of sixty-eight (68) staphylococcal isolates obtained from Philippine General Hospital (PGH) from January to March 2001 were determined employing the NCCLS recommended disc agar diffusion technique and minimum inhibitory concentration (MIC) determination of selected antimicrobials through E-test strips. Results revealed that the isolates were mostly resistant to penicillins, oxacillin and trimethoprim. About 7 percent and 67 percent of coagulase positive and coagulase negative isolates were multiple drug resistant strains. They were resistant to at least four antimicrobials tested. Resistance to wide chemical classes of drugs was demonstrated by these isolates. Levels of resistance were shown to be higher among coagulase negative than coagulase positive strains. All isolates, however, were susceptible to nitrofurantoin and vancomycin. Nonetheless, isolates with reduced susceptibility to vancomycin with MIC of 4-6 ug/mL were noted. Inducible resistance to clindamycin by erythromycin was also checked among erythromycin resistant isolates using the double-disc diffusion technique. None of the isolates tested showed lincosamide inducible resistance by the macrolide.