Antifungal metabolites from Blumea balsamifera

The leaves of Blumea balsamifera afforded icthyothereol acetate, cryptomeridiol, lutein, and β-carotene. The structures of icthyothereol acetate (1) and cryptomeridiol (2) were elucidated by extensive 1D and 2D NMR spectroscopy, while those of lutein and β-carotene were identified by comparison with...

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Bibliographic Details
Main Authors: Ragasa, Consolacion Y., Co, Angel Lyn Kristin C., Rideout, John A.
Format: text
Published: Animo Repository 2005
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/543
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Institution: De La Salle University
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Summary:The leaves of Blumea balsamifera afforded icthyothereol acetate, cryptomeridiol, lutein, and β-carotene. The structures of icthyothereol acetate (1) and cryptomeridiol (2) were elucidated by extensive 1D and 2D NMR spectroscopy, while those of lutein and β-carotene were identified by comparison with literature data. Antimicrobial tests indicated that 1 has moderate activity against the fungi Aspergillus niger, Trichophyton mentagrophytes, and Candida albicans, while 2 has low activity against A. niger, T. mentagrophytes, and C. alhicans. Both compounds have no antimicrobial activity against Psuedomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. © 2005 Taylor & Francis Ltd.