Secondary metabolites from cycas edentata

• Main Authors: Ng, Vincent Antonio S., Agoo, Esperanza Maribel G., Shen, Chien Chang, Ragasa, Consolacion Y.
• Format: text
• Published: Animo Repository 2015
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/717
• Institution: De La Salle University

© 2015, Pharmainfo Publications. All rights reserved. Objective: The study was undertaken to isolate the chemical constituents of the dichloromethane extracts of the sarcotesta, endotesta, leaflets and male cone of Cycas edentata. Methods: The compounds were isolated by silica gel chromatography and identified by nuclear magnetic resonance spectroscopy. Results: The dichloromethane extracts of C. edentata afforded β-sitosteryl-3β-glucopyranoside-6'-O-palmitate (1) from the sarcotesta; β-sitosteryl fatty acid ester (2), unsaturated fatty acid methyl esters (3), and a mixture of β-sitosterol (4a) and stigmasterol (4b) in about 5:1 ratio from the endotesta; chlorophyll a (5) from the leaflets; and triacylglycerols (6) from the male cone.The structures of 1‒6 were identified by comparison of their NMR data with those reported in the literature. Conclusion: The different parts of C. edentata yielded as a major constituent β-sitosterol which was also found in other Cycas species. β- Sitosteryl fatty acid ester isolated from the endotesta was also reported from the bark and sclerotesta. Keywords: Cycas edentata, Cycadaceae, β-sitosteryl-3β-glucopyranoside-6'-O-palmitate, β-sitosteryl fatty acid ester, β-sitosterol.