Chemical constituents of Cinnamomum cebuense

Aim: To investigate the chemical constituents of Cinnamomum cebuense, an endemic and critically endangered tree found only in Cebu, Philippines. Methods: The compounds were isolated by silica gel chromatography. The structures of the isolates were elucidated by NMR spectroscopy. Results: The dichlor...

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Main Authors: Ragasa, Consolacion Y., Espineli, Dinah L., Agoo, Esperanza Maribel G., del Fierro, Ramon S.
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Published: Animo Repository 2013
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/1218
https://animorepository.dlsu.edu.ph/context/faculty_research/article/2217/type/native/viewcontent
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Institution: De La Salle University
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Summary:Aim: To investigate the chemical constituents of Cinnamomum cebuense, an endemic and critically endangered tree found only in Cebu, Philippines. Methods: The compounds were isolated by silica gel chromatography. The structures of the isolates were elucidated by NMR spectroscopy. Results: The dichloromethane (DCM) extract of the bark of C. cebuense afforded a new monoterpene natural product 1 and a new sesquiterpene 2, along with the known compounds, 4-hydroxy-3-methoxycinnamaldehyde (3), 4-allyl-2-methoxyphenol (4), α-terpineol (5) and humulene (6). The DCM extract of the leaves of C. cebuense yielded 6, β-caryophyllene (7), squalene (8), and a mixture of α-amyrin (9), β-amyrin (10) and bauerenol (11). The structures of 1-7 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 8-11 were identified by comparison of their 13C NMR data with those reported in the literature. Conclusion: The bark of C. cebuense afforded monoterpenes, sesquiterpenes and phenolics, while the leaves yielded sesquiterpenes and triterpenes. © 2013 China Pharmaceutical University.