Immunohistochemical detection of serotonin in the small and large intestines of the domestic cat (Felis catus L.) (Carnivora: Felidae)

• Main Authors: Dimayuga, Juan Carlos C., Atienza, Melanie Anne M., Labadan, Rizza Mae L., Vitor, Rodel Jonathan S.
• Format: text
• Published: Animo Repository 2015
• Subjects: Serotonin; Immunohistochemistry; Cat > Immunology; Intestine, Large—Immunology; Biology
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/1224
• Institution: De La Salle University

Immunohistochemical detection of serotonin was performed in the small (duodenum, jejunum, ileum) and large intestines (cecum, colon and rectum) of 20 (10 male and 10 female) 2-year old domestic cats (Felis catus L.). In both organs, serotonin was observed to be reactive in the lining epithelium, enterochromaffn cells in the crypts of Lieburkuhn, smooth muscle fbers in the lamina propria, lamina muscularis mucosae and tunica muscularis, blood vessels in the lamina propria, tunica submucosa and serosa, Brunner's glands in the duodenum, Meissner's plexus in the tunica submucosa, myenteric plexus in the tunica muscularis and the lining epithelium of the tunica serosa. One main difference that has been observed is the absence of serotonin reactivity in the goblet cells. Presence of serotonin in the different segments of the intestines suggests that it can modulate the physiological processes of the intestines by exerting its effort on the different target cells.