Monoterpene glycoside and flavonoids from Blumea lacera

• Main Authors: Ragasa, Consolacion Y., Wong, Jeannie, Rideout, John A.
• Format: text
• Published: Animo Repository 2007
• Subjects: Blumea > Analysis; Anti-infective agents; Flavonoids; Monoterpenes; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/1790; https://animorepository.dlsu.edu.ph/context/faculty_research/article/2789/type/native/viewcontent
• Institution: De La Salle University

The dichloromethane extract of air-dried leaves of Blumea lacera (Asteraceae) afforded α-pinene-7β-O-β-d-2,6- diacetylglucopyranoside (1), 5,4′-dihydroxy-6,7,3′-trimethoxyflavone (2), and 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (3). Compounds 1-3 showed moderate activity against Candida albicans, low activity against Trichophyton mentagrophytes, and were inactive against Aspergillus niger. Compounds 1 and 3 indicated low activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and were inactive against Bacillus subtilis, while 2 was inactive against all four bacteria tested. © 2007 The Japanese Society of Pharmacognosy and Springer.