Antimicrobial terpenoids from Pterocarpus indicus

A mixture of loliolide 1 (> 85%) and paniculatadiol 2 (< 15%) was obtained from the ethyl acetate leaf extract of Pterocarpus indicus by silica gel chromatography, while the air-dried flowers afforded lupeol 3 and phytol esters 4. The structures of 1-4 were determined by NMR spectroscopy. Anti...

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Bibliographic Details
Main Authors: Ragasa, Consolacion Y., De Luna, Roderick D., Hofilena, Joy G.
Format: text
Published: Animo Repository 2005
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/1797
https://animorepository.dlsu.edu.ph/context/faculty_research/article/2796/type/native/viewcontent
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Institution: De La Salle University
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Summary:A mixture of loliolide 1 (> 85%) and paniculatadiol 2 (< 15%) was obtained from the ethyl acetate leaf extract of Pterocarpus indicus by silica gel chromatography, while the air-dried flowers afforded lupeol 3 and phytol esters 4. The structures of 1-4 were determined by NMR spectroscopy. Antimicrobial tests on a mixture of 1 and 2 indicated that it has moderate activity against Candida albicans and low activity against Pseudomonas aeruginosa, Escherichia coli, and Aspergillus niger. It was found inactive against Staphylococcus aureus, Bacillus subtilis, and Trichophyton mentagrophytes. © 2005 Taylor & Francis Group Ltd.