Synthesis and characterization of pyrazinamide analogs of acetylsalicylic acid and salicylic acid

• المؤلفون الرئيسيون: Alea, Glenn V., Lagua, Faith Marie G., Ajero, Michael Dominic M.
• التنسيق: text
• منشور في: Animo Repository 2017
• الموضوعات: Pyrazinamide; Salicylic acid; Tuberculosis; Aspirin; Friedel-Crafts reaction; Chemistry
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/faculty_research/1979
• المؤسسة: De La Salle University

Pyrazinamide (PZA) is one of the first-line of drugs used to treat tuberculosis. It is an important player in shortening the treatment time of the disease from almost a year to only about six months. The occurrence of resistant strains of the bacteria towards PZA threatens its effectiveness in killi...