Chemical reactivity and bioactivity properties of pyrazinamide analogs of acetylsalicylic acid and salicylic acid using conceptual density functional theory

• Main Authors: Villagracia, Al Rey C., Ong, Hui Lin, Lagua, Faith Marie G., Alea, Glenn V.
• Format: text
• Published: Animo Repository 2020
• Subjects: Pyrazinamide; Chemical reactions; Chemistry, Physical and theoretical; Tuberculosis; Density functionals; Physics
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/2214; https://animorepository.dlsu.edu.ph/context/faculty_research/article/3213/type/native/viewcontent/j.heliyon.2020.e04239
• Institution: De La Salle University

Conventional drugs used to treat Tuberculosis (TB) are becoming ineffective due to the occurrence of multiple drug resistant strains of tuberculosis (TB). This has made the TB disease a a serious global health dilemma. Hence, there is desperate necessity for the advancement of new drugs. In this wor...