Monoterpene lactones from the seeds of Nephelium lappaceum

• Main Authors: Ragasa, Consolacion Y., De Luna, Roderick D., Cruz, Wilfredo C., Rideout, John A.
• Format: text
• Published: Animo Repository 2005
• Subjects: Nephelium; Monoterpenes; Lactones; Antifungal agents; Antibacterial agents; Nuclear magnetic resonance; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/3789; https://animorepository.dlsu.edu.ph/context/faculty_research/article/4791/type/native/viewcontent/np0580053.html
• Institution: De La Salle University

Dichloromethane extracts of the seeds of Nephelium lappaceum afforded two new diastereomeric monoterpene lactones, 1 and 2, and the known butenolide siphonodin (3), as well as kaempferol 3-O-β-D-glucopyranoside-7-O-α- L-rhamnopyranoside. Compounds 1 and 2 represent a new monoterpene skeleton, and their structures were elucidated by extensive 1D and 2D NMR spectral data interpretation. Antimicrobial testing was carried out on 1 and 2 against a panel of bacteria and fungi. © 2005 American Chemical Society and American Society of Pharmacognosy.