Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression

Objective: To explore cytotoxicity of Synsepalum dulcificum (S. dulcificum) Daniell (Sapotaceae) on human colon cancer (HCT-116 and HT-29), human monocytic leukemia (THP-1) and normal (HDFn) cell lines, and its effect on the expression of early apoptotic genes, c-fos and c-jun. Methods: Leaf, stem a...

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Main Authors: Seong, Jichang, Oyong, Glenn G., Cabrera, Esperanza C.
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Published: Animo Repository 2018
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/3947
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Institution: De La Salle University