Diagnostic significance of Philadelphia chromosome BCR-ABL fusion gene detected by GTG-banding and reverse-transcription polymerase chain reaction (RT-PCR) in Filipino patients with chronic myelogenous leukemia (CML)

• Main Authors: Amarillo, Ferdinand F., Enriquez, Ma. Luisa D.
• Format: text
• Published: Animo Repository 2003
• Subjects: Chronic myeloid leukemia > Philippines; Polymerase chain reaction; Hemic and Lymphatic Diseases
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/4147
• Institution: De La Salle University

Introduction. Chronic myelogenous leukemia (CML) is a good clinicla model for showing the capabilities and limitations of cytogenetic and molecular tools in the detection and progress surveillance of the disease. Its hallmark at the level of the chromosomes is the reciprocal translocation of chromos...