Proto-ubiquitin: A Bayesian prediction of an ancient protein during the prokaryotic-eukaryotic transition

• Main Authors: Deocaris, Custer C., Cunanan, Lovette F., Galapia, Richelda A., Endriga, Marla A.
• Format: text
• Published: Animo Repository 2011
• Subjects: Ubiquitin; Proteins—Evolution; Biochemistry, Biophysics, and Structural Biology; Biology
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/5482
• Institution: De La Salle University

Only recently have biologists been able to apply mathematical and biochemical tools to preview lifestyles of ancient life forms and "travel back in time." In this paper, we describe an ancestral reconstruction of ubiquitin to determine its molecular properties during the rise of the eukary...