Segmental duplications: A possible mechanism of hominid uplift through microRNA diversification

• Main Authors: Endriga, Maria A., Burog, Aldrich Ivan Lois D., Dalmacion, Denise Lauren V., Deocaris, Custer C.
• Format: text
• Published: Animo Repository 2010
• Subjects: MicroRNA; Evolutionary genetics; Mutation (Biology); Biochemistry, Biophysics, and Structural Biology; Biology
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/5452
• Institution: De La Salle University

MicroRNAs (miRNA) are ~21 nucleotide-long gene silencers. Segmental duplications (SD) are among the driving forces in acquiring new genes. Both miRNA and SD are believed to have played a significant role in evolution, particularly in the divergence of humans (Homo sapiens) from the chimpanzee (Pan t...