Characterization of the putative active site of mycobacterium tuberculosis pyrazinamidase: An application of bioinformatics software for modeling, docking and testing of drug analogues
Pyrazinamide (PZA), a first-line pro-drug targeting Mycobacterium tuberculosis (Mtb), is a cornerstone in tuberculosis combined therapeutic management. It is converted to Pyrazinoic acid by Pyrazinamidase (PZAse), a 2kD enzyme encoded by pncA gene. Ongoing search for drug analogues of Pyrazinamide e...
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| Main Authors: | , |
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| Format: | text |
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Animo Repository
2014
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| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/6096 |
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| Institution: | De La Salle University |