Mathematical modeling of APP processing influenced by SORLA in Alzheimer's disease: Two pilot models

• 主要作者: Lao, Angelyn R.
• 格式: text
• 出版: Animo Repository 2010
• 主題: Amyloid beta-protein precursor—Mathematical models; Alzheimer's disease; Mathematics
• 在線閱讀: https://animorepository.dlsu.edu.ph/faculty_research/7456
• 機構: De La Salle University

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by amyloid plaques in the brain of affected individuals. This project aims at modeling of neurodegenerative processes in AD.· Our study focuses on the interactome of neuronal factors central to the proteolytic processing of...