Multi-compartmental modeling of APP processing influenced by SORLA in Alzheimer’s disease

• المؤلف الرئيسي: Lao, Angelyn R.
• التنسيق: text
• منشور في: Animo Repository 2012
• الموضوعات: Amyloid beta-protein precursor—Mathematical models; Alzheimer's disease; Mathematics
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/faculty_research/7440

The formation of Aβ plaques from the processing of amyloid precursor protein (APP) is central to the pathology of Alzheimer’s disease. Studies concerning APP processing are conventionally conducted in a single-compartment, where the reactants involved are either in a monomeric or a dimeric form of A...