Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A

Hazardous mycotoxins such as Ochratoxin A (OTA) can cause negative impacts on both human and animal health and may lead to chronic diseases. Therefore, detection of OTA is important to reduce foodborne disease occurrence. The conventional methods for detection of Ochratoxins has some drawbacks such...

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Main Authors: Abdullah, N.S.F., Singh, B.S.M., Saheed, M.S.M.
Format: Conference or Workshop Item
Published: American Institute of Physics Inc. 2023
Online Access:http://scholars.utp.edu.my/id/eprint/37556/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163858432&doi=10.1063%2f5.0116927&partnerID=40&md5=b79d30658dce057fd8a194de5ff97699
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Institution: Universiti Teknologi Petronas
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spelling oai:scholars.utp.edu.my:375562023-10-04T13:32:38Z http://scholars.utp.edu.my/id/eprint/37556/ Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A Abdullah, N.S.F. Singh, B.S.M. Saheed, M.S.M. Hazardous mycotoxins such as Ochratoxin A (OTA) can cause negative impacts on both human and animal health and may lead to chronic diseases. Therefore, detection of OTA is important to reduce foodborne disease occurrence. The conventional methods for detection of Ochratoxins has some drawbacks such as time-consuming procedure, high cost and sophisticated equipment. Currently, biosensor with the integration of nanomaterials has becomes a promising tool to overcome the limitations of the previous methods and Graphene is broadly explored due to its high electrical conductivity, expansive surface region and has unique heterogeneous electron transfer rate. Herein, the Water based Graphene paste which is free from harmful organic solvents with good conductivity, and good adhesion with Screen Printed Electrode (SPE) was prepared for Ochratoxin A biosensor. The graphene film is then coated with chemical linkers and biorecognition element. The performance of the stepwise modification of the bioelectrodes was carried out by using electrochemical impedance spectroscopy. Fourier-transform infrared peak shifts clearly shows the successful functionalization of the graphene film. A linear increment trend is observed as the Rct value rises in response to interactions with increasing concentrations of OTA mycotoxin ranging from 1 fg ml-1 to 1 ng ml-1. Overall, this biosensor offers a quick, low-cost, and a simple approach to determine OTA in food and feed samples. © 2023 American Institute of Physics Inc.. All rights reserved. American Institute of Physics Inc. 2023 Conference or Workshop Item NonPeerReviewed Abdullah, N.S.F. and Singh, B.S.M. and Saheed, M.S.M. (2023) Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A. In: UNSPECIFIED. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163858432&doi=10.1063%2f5.0116927&partnerID=40&md5=b79d30658dce057fd8a194de5ff97699 10.1063/5.0116927 10.1063/5.0116927 10.1063/5.0116927
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Institutional Repository
url_provider http://eprints.utp.edu.my/
description Hazardous mycotoxins such as Ochratoxin A (OTA) can cause negative impacts on both human and animal health and may lead to chronic diseases. Therefore, detection of OTA is important to reduce foodborne disease occurrence. The conventional methods for detection of Ochratoxins has some drawbacks such as time-consuming procedure, high cost and sophisticated equipment. Currently, biosensor with the integration of nanomaterials has becomes a promising tool to overcome the limitations of the previous methods and Graphene is broadly explored due to its high electrical conductivity, expansive surface region and has unique heterogeneous electron transfer rate. Herein, the Water based Graphene paste which is free from harmful organic solvents with good conductivity, and good adhesion with Screen Printed Electrode (SPE) was prepared for Ochratoxin A biosensor. The graphene film is then coated with chemical linkers and biorecognition element. The performance of the stepwise modification of the bioelectrodes was carried out by using electrochemical impedance spectroscopy. Fourier-transform infrared peak shifts clearly shows the successful functionalization of the graphene film. A linear increment trend is observed as the Rct value rises in response to interactions with increasing concentrations of OTA mycotoxin ranging from 1 fg ml-1 to 1 ng ml-1. Overall, this biosensor offers a quick, low-cost, and a simple approach to determine OTA in food and feed samples. © 2023 American Institute of Physics Inc.. All rights reserved.
format Conference or Workshop Item
author Abdullah, N.S.F.
Singh, B.S.M.
Saheed, M.S.M.
spellingShingle Abdullah, N.S.F.
Singh, B.S.M.
Saheed, M.S.M.
Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A
author_facet Abdullah, N.S.F.
Singh, B.S.M.
Saheed, M.S.M.
author_sort Abdullah, N.S.F.
title Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A
title_short Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A
title_full Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A
title_fullStr Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A
title_full_unstemmed Highly Conductive Graphene Paste as Sensing Element for Detection of Ochratoxin A
title_sort highly conductive graphene paste as sensing element for detection of ochratoxin a
publisher American Institute of Physics Inc.
publishDate 2023
url http://scholars.utp.edu.my/id/eprint/37556/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163858432&doi=10.1063%2f5.0116927&partnerID=40&md5=b79d30658dce057fd8a194de5ff97699
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