Metformin as Targeted Treatment in Fragile X Syndrome

• Main Authors: Dy, Angel Belle C, Tassone, F, Eldeeb, M, Salcedo-Arellano, M.J, Tartaglia, N, Hagerman, R
• Format: text
• Published: Archīum Ateneo 2017
• Subjects: fragile X syndrome; metformin; obesity; Prader‐Willi‐phenotype; targeted treatments; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Medicine and Health Sciences; Public Health
• Online Access: https://archium.ateneo.edu/asmph-pubs/23; https://onlinelibrary.wiley.com/doi/full/10.1111/cge.13039
• Institution: Ateneo De Manila University

Background Individuals with fragile X syndrome (FXS) have both behavioral and medical comorbidities and the latter include obesity in approximately 30% and the Prader‐Willi Phenotype (PWP) characterized by severe hyperphagia and morbid obesity in less than 10%. Metformin is a drug used in individual...