Schistosoma japonicum cathepsin B as potential diagnostic antigen for Asian zoonotic schistosomiasis

• Main Authors: Macalanda, Adrian Miki C, Angeles, Jose Ma. M, Moendeg, Kharleezelle J, Dang-Trinh, Minh-Anh, Higuchi, Luna, Kirinoki, Masashi, Chigusa, Yuichi, Leonardo, Lydia R, Villacorte, Elena A, Rivera, Pilarita T, Goto, Yasuyuki, Kawazu, Shin-ichiro
• Format: text
• Published: Archīum Ateneo 2019
• Subjects: Biology; Parasitic Diseases
• Online Access: https://archium.ateneo.edu/biology-faculty-pubs/30; https://link.springer.com/article/10.1007/s00436-019-06410-x
• Institution: Ateneo De Manila University

In this study, the diagnostic value of Schistosoma japonicum cathepsin B (SjCatB) was evaluated as an antigen for the early detection of S. japonicum infection. SjCatB is a key protease used by the cercaria to penetrate the intact skin of the host for transdermal infection. The early exposure of the...