Sustained DDB-2 and TRX Transcriptional Response of Quercetin-Treated Lymphocytes Exposed to Co-60 Radiation

• Main Authors: Caraos, Gloriamaris L, Manrique, Mary Jayne C, Feliciano, Chitho P, Tan Gana, Neil H, Ramos, Maria Cristina R
• Format: text
• Published: Archīum Ateneo 2019
• Subjects: DDB-2; Flavonoid; Gamma radiation; Quercetin; Real-time PCR; TRX; Biology; Genetics and Genomics
• Online Access: https://archium.ateneo.edu/biology-faculty-pubs/102; https://www.sciencedirect.com/science/article/pii/S2452014419300585?via%3Dihub
• Institution: Ateneo De Manila University

The flavonoid quercetin has been previously studied for its radioprotective and anti-cancer properties. However, none so far have described the transcriptional changes that occur in radiation-induced genes in the presence of quercetin. The objectives of the study were to demonstrate the effect of qu...