Angio-Suppressive Effect of Sterols from Ardisia Pyramidalis (Cav.) Pers.

• Main Authors: Raga, Dennis D, Herrera, Annabelle A, Alimboyoguen, Agnes B, Shen, Chien-Chang, Ragasa, Consolacion Y
• Format: text
• Published: Archīum Ateneo 2017
• Subjects: Ardisia pyramidalis; spinasterol; spinasteryl acetate; angiogenesis; chorioallantoic membrane (CAM); CAM assay; Biology; Pharmacology, Toxicology and Environmental Health
• Online Access: https://archium.ateneo.edu/biology-faculty-pubs/107; https://link.springer.com/article/10.1007/s11094-017-1674-4
• Institution: Ateneo De Manila University

Spinasterol (1) and spinasteryl acetate (2) from the leaves of Ardisia pyramidalis (Cav.) Pers. (Myrsinaceae) were tested on duck chorioallantoic membrane (CAM) vascularity assay. The petechial to severe hemorrhaging, hyperemia, and the formation of ghost vessels were observed in CAMs treated with c...